一、产品简介

abcam山羊源Iba1多抗(ab5076)在染色和免疫组织化学中通常被用作小胶质细胞激活的标记物，因为电离钙结合适配器分子1 (Iba1)是一种具有肌动蛋白捆绑活性的小胶质细胞/巨噬细胞特异性钙结合蛋白，参与激活的小胶质细胞的膜褶化和吞噬。

二、产品属性

宿主：Goat

特异性：ab5076 is expected to recognize the isoforms represented by NP_001614 and NP_116573 but not NP_004838. 

Although we received several excellent papers on ab5076 working with rat IHC-P, rat is not a batch tested species for IHC-P and we cannot guarantee.

应用：IHC-P, WB

种属反应：Rat, Human（可预测用于：Pig, Macaque monkey）

免疫原：Synthetic peptide corresponding to Human Iba1 aa 135-147 (C terminal). Accession Number(s): NP_116573.1; NP_001614.3

三、产品引用文献

1. Miao X  et al. SARM1 Promotes Neurodegeneration and Memory Impairment in Mouse Models of Alzheimer's Disease. Aging Dis 15:390-407 (2024).

2. Chen R  et al. Thioredoxin1 Binding Metastasis-Associated Lung Adenocarcinoma Transcript 1 Attenuates Inflammation and Apoptosis after Intracerebral Hemorrhage. Aging Dis 15:1384-1397 (2024).

3. Adzic Bukvic M  et al. Expression of functionally distinct ecto-5'-nucleotidase/CD73 glycovariants in reactive astrocytes in experimental autoimmune encephalomyelitis and neuroinflammatory conditions in vitro. Glia 72:19-33 (2024).

更多有关abcam山羊源Iba1多抗(ab5076)的信息，请联系abcam抗体供应商——北京百奥创新科技有限公司！