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Clone Name
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UMAB95
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Applications
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10k-ChIP, IF, IHC, WB
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Recommend Dilution
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WB 1:500, IHC 1:100
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Reactivity
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Human, Monkey, Mouse, Rat
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Host
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Mouse
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Clonality
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Monoclonal
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Immunogen
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Full length human recombinant protein of human EGFR(NP_958440) produced in HEK293T cell.
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Formulation
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PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
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Concentration
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0.5~1.0 mg/ml (Lot Dependent)
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Purification
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Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
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Conjugation
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Unconjugated
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Storage Condition
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Store at -20°C as received.
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Predicted Protein Size
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42.4 kDa
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Gene Name
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Homo sapiens epidermal growth factor receptor (EGFR), transcript variant 3, mRNA.
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Background
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The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. Multiple alternatively spliced transcript variants that encode different protein isoforms have been found for this gene. [provided by RefSeq, Jul 2010]
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Synonyms
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ERBB; ERBB1; ERRP; HER1; mENA; NISBD2; PIG61
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