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Clone Name
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UMAB43
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Applications
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IF, IHC, WB
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Recommend Dilution
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WB 1:500, IHC 1:400, IF 1:100
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Reactivity
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Human, Mouse, Rat, Monkey, Dog
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Host
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Mouse
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Clonality
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Monoclonal
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Immunogen
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Full length human recombinant protein of human ALDH1L1 (NP_036322) produced in HEK293T cell.
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Formulation
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PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
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Concentration
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0.5~1.0 mg/ml (Lot Dependent)
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Purification
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Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
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Conjugation
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Unconjugated
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Storage Condition
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Store at -20°C as received.
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Predicted Protein Size
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98.6 kDa
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Gene Name
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Homo sapiens aldehyde dehydrogenase 1 family member L1 (ALDH1L1), transcript variant 2, mRNA.
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Background
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The protein encoded by this gene catalyzes the conversion of 10-formyltetrahydrofolate, nicotinamide adenine dinucleotide phosphate (NADP+), and water to tetrahydrofolate, NADPH, and carbon dioxide. The encoded protein belongs to the aldehyde dehydrogenase family. Loss of function or expression of this gene is associated with decreased apoptosis, increased cell motility, and cancer progression. There is an antisense transcript that overlaps on the opposite strand with this gene locus. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2012]
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Synonyms
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10-fTHF; 10-FTHFDH; FDH; FTHFD
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