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人虹膜色素上皮细胞
  • 品牌:Accegen
  • 产地:美国
  • 型号:1 vial
  • 货号:ABC-TC3658
  • 发布日期: 2022-09-21
  • 更新日期: 2024-08-12
产品详请
产地 美国
保存条件 Dry Ice
品牌 Accegen
货号 ABC-TC3658
用途 详询
组织来源 详询
细胞形态 详询
是否是肿瘤细胞
保质期 详询
器官来源 详询
免疫类型 详询
品系 详询
生长状态 详询
物种来源 详询
包装规格 1 vial
是否进口
product name:Human Iris Pigment Epithelial Cells;
cat no:ABC-TC3658;
Size/Quantity:1 vial;
Biosafety Level:1;
Shipping Info:Dry Ice;
Storage:Liquid Nitrogen;
Description:The iris is a pigmented disk with a variable aperture which forms the pupil of the eye. It is covered by squamous epithelium on anterior surface and 2 layers of pigmented epithelium on posterior. The iris pigment epithelial cells (IPE) share functional properties with retinal pigment epithelial cells (RPE) such as phagocytosis, degradation of rod outer segments and synthesis of trophic factors. In recent years, IPE have been transplanted into the subretinal space of eye to treat RPE defects. The grafted IPE were seen to survive for months. There was a remodeling of cellular layers in the subretinal space over time where grafted IPE joined the native RPE. The cellular response that developed exhibited macrophages and were similar to that observed following RPE transplantation. In vitro study also show that IPE expressing CD86, directly suppresses T cell activation via binding to cytotoxic T lymphocyte-associated antigen 4.HIPEpiC from AcceGen Research Laboratories are isolated from the human iris. HIPEpiC are cryopreserved at passage one and delivered frozen. Each vial contains >5×10^5 cells in 1 ml volume. HIPEpiC are characterized by immunofluorescent method with antibodies to cytokeratin-18, vimentin and fibronectin. HIPEpiC are negative for HIV-1, HBV, HCV, mycoplasma, bacteria, yeast and fungi. HIPEpiC are guaranteed to further expand for two passages (around 10 population doublings) in the conditions provided by AcceGen Research Laboratories.;
Quality Control:All cells test negative for mycoplasma, bacteria, yeast, and fungi;
Application:For research use only.
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生物样本运输;

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