- 品牌:赛默飞
- 产地:国外
- 型号:详询
- 货号:PA5-116785
- 发布日期: 2022-08-29
- 更新日期: 2024-08-12
产地 | 国外 |
品牌 | 赛默飞 |
货号 | PA5-116785 |
保存条件 | -20° C, Avoid Freeze/Thaw Cycles |
用途 | 详询 |
应用范围 | ICC/IF WB IHC (P) |
抗原来源 | 详询 |
CAS编号 | |
保质期 | 详询 |
抗体名 | Histone H3ac (pan-acetyl) Polyclonal Antibody |
是否单克隆 | 否 |
克隆性 | 是 |
靶点 | 详询 |
适应物种 | Human, Mouse, Rat |
形态 | Liquid |
宿主 | Rabbit |
标记物 | 详询 |
包装规格 | 详询 |
纯度 | 详询% |
亚型 | IgG |
标识物 | 详询 |
浓度 | 1.1 mg/mL% |
免疫原 | 详询 |
是否进口 | 是 |
产品信息
应用 |
建议稀释比 |
免疫印迹 (WB) |
1:500-1:2,000 |
免疫组化(石蜡) (IHC (P)) |
1:50-1:200 |
免疫细胞化学 (ICC/IF) |
1:50-1:200 |
产品规格
|
|
---|---|
种属反应 |
Human, Mouse, Rat |
宿主/亚型 |
Rabbit / IgG |
分类 |
Polyclonal |
类型 |
Antibody |
抗原 |
A synthetic peptide of human Acetyl-Histone H3-K9/K14/K18/K23/K27 |
偶联物 |
Unconjugated |
形式 |
Liquid |
浓度 |
1.1 mg/mL |
纯化类型 |
Affinity chromatography |
保存液 |
PBS, pH 7.3, with 50% glycerol |
内含物 |
0.02% sodium azide |
保存条件 |
-20° C, Avoid Freeze/Thaw Cycles |
RRID |
AB_2901416 |
产品详细信息
Positive Samples: HeLa, NIH/3T3, C6
靶标信息
Histone H3 is one of the DNA-binding proteins found in the chromatin of all eukaryotic cells. H3 along with four core histone proteins binds to DNA forming the structure of the nucleosome. Histones play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. Post translationally, histones are modified in a variety of ways to either directly change the chromatin structure or allow for the binding of specific transcription factors. The N-terminal tail of histone H3 protrudes from the globular nucleosome core and can undergo several different types of post-translational modifications that influence cellular processes. These modifications include the covalent attachment of methyl or acetyl groups to lysine and arginine amino acids and the phosphorylation of serine or threonine.