产品描述: 赞鲁替尼 ，也被称为BGB-3111，是一种有效且高度选择性的小分子BTK抑制剂，可用于多种淋巴瘤的潜在 。BGB-3111选择性地结合并抑制BTK的活性，并阻止B细胞抗原受体（BCR）信号通路的激活。扎努布替尼具有S-异构体CAS 1691249-45-2。

产品名称: Zanubrutinib
CAS#: 1691249-45-2 (S-isomer)
分子式: C27H29N5O3
Exact Mass: 471.227
分子量: 471.561
元素分析: C, 68.77; H, 6.20; N, 14.85; O, 10.18

Synonym: BGB-3111; BGB 3111; BGB3111; Zanubrutinib; Brukinsa.

IUPAC/Chemical Name: (7S)-4,5,6,7-Tetrahydro-7-[1-(1-oxo-2-propen-1-yl)-4-piperidinyl]-2-(4-phenoxyphenyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide

InChi Key: RNOAOAWBMHREKO-QFIPXVFZSA-N

InChi Code: InChI=1S/C27H29N5O3/c1-2-23(33)31-16-13-18(14-17-31)22-12-15-29-27-24(26(28)34)25(30-32(22)27)19-8-10-21(11-9-19)35-20-6-4-3-5-7-20/h2-11,18,22,29H,1,12-17H2,(H2,28,34)/t22-/m0/s1

SMILES Code: O=C(C1=C2NCC[C@@H](C3CCN(C(C=C)=O)CC3)N2N=C1C4=CC=C(OC5=CC=CC=C5)C=C4)N

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001