产品描述：吉非替尼又名ZD1839，是一种具有抗cancer活性的苯胺基喹唑啉。吉非替尼抑制包括EGFR在内的多种酪氨酸激酶的催化活性。具体而言，该试剂与ATP与EGFR酪氨酸激酶结构域的结合竞争，从而抑制受体自磷酸化并导致信号转导的抑制。吉非替尼还可能诱导细胞周期停滞。它由阿斯利康和Teva销售。

产品名称: Gefitinib
CAS#: 184475-35-2
分子式: C22H24ClFN4O3
分子量: 446.9
元素分析: C, 59.13; H, 5.41; Cl, 7.93; F, 4.25; N, 12.54; O, 10.74

Synonym: ZD 1839; ZD1839; ZD-1839; Gefitinib; US brand name: Iressa.

IUPAC/Chemical Name: N-(3-chloro-4-fluorophenyl)-7-methoxy-6-(3-morpholinopropoxy)quinazolin-4-amine

InChi Key: XGALLCVXEZPNRQ-UHFFFAOYSA-N

InChi Code: InChI=1S/C22H24ClFN4O3/c1-29-20-13-19-16(12-21(20)31-8-2-5-28-6-9-30-10-7-28)22(26-14-25-19)27-15-3-4-18(24)17(23)11-15/h3-4,11-14H,2,5-10H2,1H3,(H,25,26,27)

SMILES Code: COC1=CC2=NC=NC(NC3=CC=C(F)C(Cl)=C3)=C2C=C1OCCCN4CCOCC4

Appearance: white solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO, not in water

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001