Description: DSPE has been used in an FDA approved liposomal drug. It is the staring material for the synthesis of mPEG-DSPE, a widely used surface modifying amphiphilic molecule that keeps liposomes from interacting with blood components and provides a long circulation time for liposomes and other nanoparticles. DSPE has been explored to construct liposomes that are stable and long circulating in blood, but promptly release its content after ultrasound sonication.

Name: DSPE
CAS#: 1069-79-0
Chemical Formula: C41H82NO8P
Exact Mass: 747.5778
Molecular Weight: 748.08
Elemental Analysis: C, 65.83; H, 11.05; N, 1.87; O, 17.11; P, 4.14

Synonym: DSPE; 1,2-Distearoyl-sn-glycero-3-Phosphoethanolamine 1,2-DSPE

IUPAC/Chemical Name: 1,2-Distearoyl-sn-glycero-3-phosphoethanolamine

InChi Key: LVNGJLRDBYCPGB-LDLOPFEMSA-N

InChi Code: InChI=1S/C41H82NO8P/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-40(43)47-37-39(38-49-51(45,46)48-36-35-42)50-41(44)34-32-30-28-26-24-22-20-18-16-14-12-10-8-6-4-2/h39H,3-38,42H2,1-2H3,(H,45,46)/t39-/m1/s1

SMILES Code: CCCCCCCCCCCCCCCCCC(O[C@@H](COP(O)(OCCN)=O)COC(CCCCCCCCCCCCCCCCC)=O)=O

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001