Description: DSPC has been used in many FDA approved liposomal drugs including COVID 19 vaccines. It is a phospholipid containing the saturated long-chain (18:0) stearic acid inserted at the sn-1 and sn-2 positions. It is commonly used in the generation of micelles, liposomes, and other types of artificial membranes. DSPC has a relatively high main phase transition temperature (55.6 °C). DSPC has been widely used to construct liposomes, including, Lipo-Dox®, DaunoXome®, Vyxeos®, and ONPATTRO®. In some cases, DSPC and HSPC are interchangeable.

Name: DSPC
CAS#: 816-94-4
Chemical Formula: C44H88NO8P
Exact Mass: 789.6248
Molecular Weight: 790.16
Elemental Analysis: C, 66.88; H, 11.23; N, 1.77; O, 16.20; P, 3.92

Synonym: DSPC; 1,2-Distearoyl-sn-glycero-3-PC; Coatsome MC 8080;

IUPAC/Chemical Name: 1,2-Distearoyl-sn-glycero-3-phosphocholine

InChi Key: NRJAVPSFFCBXDT-HUESYALOSA-N

InChi Code: InChI=1S/C44H88NO8P/c1-6-8-10-12-14-16-18-20-22-24-26-28-30-32-34-36-43(46)50-40-42(41-52-54(48,49)51-39-38-45(3,4)5)53-44(47)37-35-33-31-29-27-25-23-21-19-17-15-13-11-9-7-2/h42H,6-41H2,1-5H3/t42-/m1/s1

SMILES Code: CCCCCCCCCCCCCCCCCC(O[C@@H](COP([O-])(OCC[N+](C)(C)C)=O)COC(CCCCCCCCCCCCCCCCC)=O)=O

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001