Description: Camptothecin sodium selectively inhibits the nuclear enzyme DNA Topoisomerase, Type I. Several semisynthetic analogs of camptothecin have demonstrated antitumor activity.

Name: Camptothecin sodium
CAS#: 25387-67-1
Chemical Formula: C20H17N2NaO5
Exact Mass: 388.1035
Molecular Weight: 388.35
Elemental Analysis: C, 61.86; H, 4.41; N, 7.21; Na, 5.92; O, 20.60

Synonym: 20(S)-Camptothecin sodium salt, AI3-62931, Camptothecine sodium, Camptothecin, sodium salt, Camptothecin sodium, NSC-100880, Sodium camptothecin

IUPAC/Chemical Name: Indolizino(1,2-b)quinoline-7-acetic acid, alpha-ethyl-9,11-dihydro-alpha-hydroxy-8-(hydroxymethyl)-9-oxo-, monosodium salt, (S)- (9CI)

InChi Key: HVGXXVCXEMRSLD-BDQAORGHSA-N

InChi Code: 1S/C20H15N2O4.Na/c1-2-20(25)14-8-16-17-12(7-11-5-3-4-6-15(11)21-17)9-22(16)18(23)13(14)10-26-19(20)24;/h3-8H,2,9-10H2,1H3;/q-1;+1/t20-;/m0./s1

SMILES Code: CC[C@@]1(c2cc-3n(c(=O)c2COC1=O)Cc4c3nc5ccccc5c4)[O-].[Na+]

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001