Description: Acid-PEG1-t-butyl ester is a PEG derivative containing a t-butyl protected carboxyl group with a terminal carboxylic acid. The terminal carboxylic acid can be reacted with primary amine groups in the presence of activators (e.g. EDC, or DCC) to form a stable amide bond. The hydrophilic PEG spacer increases solubility in aqueous media. The t-butyl protected carboxyl group can be deprotected under acidic conditions.

Name: Acid-PEG1-t-butyl ester
CAS#: 2086689-08-7
Chemical Formula: C10H18O5
Exact Mass: 218.1154
Molecular Weight: 218.25
Elemental Analysis: C, 55.03; H, 8.31; O, 36.65

Synonym: Acid-PEG1-t-butyl ester

IUPAC/Chemical Name: 3-(3-(tert-butoxy)-3-oxopropoxy)propanoic acid

InChi Key: ZDYGOKORAHMWLC-UHFFFAOYSA-N

InChi Code: InChI=1S/C10H18O5/c1-10(2,3)15-9(13)5-7-14-6-4-8(11)12/h4-7H2,1-3H3,(H,11,12)

SMILES Code: OC(CCOCCC(OC(C)(C)C)=O)=O

Appearance: Solid powder

Purity: >95% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.03.00