Description: TB5 is a MAO-B inhibitor. TB5 showed the inhibitory activity and selectivity toward hMAO-B, with Ki and SI values of 0.11±0.01?μm and 13.18, respectively. TB5 was found to be nontoxic at 5 and 25?μm, with 95.75 and 84.59?% viability among cells, respectively.

Name: TB5
CAS#: 948841-07-4
Chemical Formula: C15H14BrNOS
Exact Mass: 334.9979
Molecular Weight: 336.247
Elemental Analysis: C, 53.58; H, 4.20; Br, 23.76; N, 4.17; O, 4.76; S, 9.53

Synonym: TB5, TB 5, TB-5

IUPAC/Chemical Name: (2E)-1-(5-bromothiophen-2-yl)-3-[4-(dimethylamino)phenyl]prop-2-en-1-one

InChi Key: PTLDLBSWTKNYCY-VMPITWQZSA-N

InChi Code: InChI=1S/C15H14BrNOS/c1-17(2)12-6-3-11(4-7-12)5-8-13(18)14-9-10-15(16)19-14/h3-10H,1-2H3/b8-5+

SMILES Code: O=C(C1=CC=C(Br)S1)/C=C/C2=CC=C(N(C)C)C=C2

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001