Description: STING agonist 12b is an agonist of stimulator of interferon genes (STING). It binds to STING and induces interferon reporter gene expression in cells expressing human or mouse STING. STING agonist 12b induces expression of TNF-a, IL-6, IP-10, and IL-1b in THP-1 cells.

Name: STING Agonist 12b
CAS#: 2411100-70-2
Chemical Formula: C16H15NO2
Exact Mass: 253.1103
Molecular Weight: 253.301
Elemental Analysis: C, 75.87; H, 5.97; N, 5.53; O, 12.63

Synonym: STING Agonist 12b; STING Agonist-12b;

IUPAC/Chemical Name: 2-methoxy-5,6-dimethylacridin-9(10H)-one

InChi Key: SEVGTQHWWAYAQR-UHFFFAOYSA-N

InChi Code: InChI=1S/C16H15NO2/c1-9-4-6-12-15(10(9)2)17-14-7-5-11(19-3)8-13(14)16(12)18/h4-8H,1-3H3,(H,17,18)

SMILES Code: O=C1C2=CC=C(C(C)=C2NC3=CC=C(OC)C=C13)C

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001