Description: SR12343 is an inhibitor of tumor necrosis factor α (TNF-α)- and lipopolysaccharide (LPS)-induced NF-κB activation by blocking the interaction between IKKβ and NEMO, suppressing LPS-induced acute pulmonary inflammation in mice.

Name: SR12343
CAS#: 2055101-86-3
Chemical Formula: C15H15BrClN3O
Exact Mass: 367.0087
Molecular Weight: 368.66
Elemental Analysis: C, 48.87; H, 4.10; Br, 21.67; Cl, 9.62; N, 11.40; O, 4.34

Synonym: SR-12343; SR 12343; SR12343

IUPAC/Chemical Name: N-(3-Bromophenethyl)-2-((5-chloropyridin-2-yl)amino)acetamide

InChi Key: PEOFCAIUELALCR-UHFFFAOYSA-N

InChi Code: InChI=1S/C15H15BrClN3O/c16-12-3-1-2-11(8-12)6-7-18-15(21)10-20-14-5-4-13(17)9-19-14/h1-5,8-9H,6-7,10H2,(H,18,21)(H,19,20)

SMILES Code: O=C(NCCC1=CC=CC(Br)=C1)CNC2=NC=C(Cl)C=C2

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.03.00