Description: SM-7368 inhibits TNF-alpha-induced MMP-9 upregulation in a concentration-dependent manner. SM-7368 strongly inhibits the TNF-alpha-induced invasion of HT1080 human fibrosarcoma cell line.

Synonym: SM-7368; SM 7368; SM7368; NF-kappaB Activation Inhibitor III

IUPAC/Chemical Name: 3-Chloro-4-nitro-N-(5-nitro-1,3-thiazol-2-yl)benzamide

InChi Key: XCHLNGBTHLJLFG-UHFFFAOYSA-N

InChi Code: InChI=1S/C10H5ClN4O5S/c11-6-3-5(1-2-7(6)14(17)18)9(16)13-10-12-4-8(21-10)15(19)20/h1-4H,(H,12,13,16)

SMILES Code: O=C(NC1=NC=C([N+]([O-])=O)S1)C2=CC=C([N+]([O-])=O)C(Cl)=C2

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001