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Simvastatin
  • 品牌:MedKoo
  • 产地:美国
  • 货号:318694
  • cas:79902-63-9
  • 发布日期: 2022-07-20
  • 更新日期: 2024-08-12
产品详请
产地 美国
品牌 MedKoo
货号 318694
用途 This product is for research use only, not for human or veterinary use.
包装规格 10.0g; 20.0g; 50.0g; 100.0g; 200.0g; 1.0kg;
CAS编号 79902-63-9
纯度 >98%%
是否进口

Description: Simvastatin is a competitive inhibitor of HMG-CoA reductase. This compound has been shown to modulate purified bovine pituitary 20 S proteasome via mild stimulation of chymotrypsin-like activity and inhibition of peptidylglutamylpeptide hydrolyzing activity. Simvastatin is marketed under the trade name Zocor™ and is often prescribed in combination with ezetimibe to treat dyslipidemia. This drug combination is known commercially as Vytorin or Inegy.

Synonym: Simvastatin; Zocor; Synvinolin; MK-733; Sinvacor; MK 733; MK-733; MK733.

IUPAC/Chemical Name: (1S,3R,7S,8S)-8-(2-((2R,4R)-4-hydroxy-6-oxotetrahydro-2H-pyran-2-yl)ethyl)-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl 2,2-dimethylbutanoate

InChi Key: RYMZZMVNJRMUDD-OVOOIQHOSA-N

InChi Code: InChI=1S/C25H38O5/c1-6-25(4,5)24(28)30-21-12-15(2)11-17-8-7-16(3)20(23(17)21)10-9-19-13-18(26)14-22(27)29-19/h7-8,11,15-16,18-21,23,26H,6,9-10,12-14H2,1-5H3/t15-,16-,18+,19+,20-,21-,23?/m0/s1

SMILES Code: C[C@H]1C=CC2=C[C@H](C)C[C@H](OC(C(C)(C)CC)=O)C2[C@H]1CC[C@@H]3C[C@@H](O)CC(O3)=O

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO, not in water

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001