Description: SD-1008 is an inhibitor of the JAK2/STAT3 signaling pathway. SD-1008 induces apoptosis in cell lines expressing constitutively active tyrosine-phosphorylated STAT3

Name: SD-1008
CAS#: 960201-81-4
Chemical Formula: C18H19NO5
Exact Mass: 329.1263
Molecular Weight: 329.35
Elemental Analysis: C, 65.64; H, 5.82; N, 4.25; O, 24.29

Synonym: SD 1008; SD1008; SD-1008

IUPAC/Chemical Name: (1R,5R,6S,7R)-dimethyl 8-benzyl-2-oxo-8-azabicyclo[3.2.1]oct-3-ene-6,7-dicarboxylate

InChi Key: PYZQFEIRZQYUJQ-MIGQKNRLSA-N

InChi Code: InChI=1S/C18H19NO5/c1-23-17(21)14-12-8-9-13(20)16(15(14)18(22)24-2)19(12)10-11-6-4-3-5-7-11/h3-9,12,14-16H,10H2,1-2H3/t12-,14-,15-,16+/m1/s1

SMILES Code: O=C([C@H]1[C@@H]2C(C=C[C@@H](N2CC3=CC=CC=C3)[C@H]1C(OC)=O)=O)OC

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001