Description: SC-51322 is a selective EP1 antagonist that inhibits PGE2 signaling in a guinea pig ileum muscle strip assay with a pA2 value of 8.1 and demonstrates analgesic activity in a mouse writhing assay with an ED50 value of 0.9 mg/kg.

Synonym: SC-51322; SC 51322; SC51322.

IUPAC/Chemical Name: 3-chloro-N'-[3-(furan-2-ylmethylsulfanyl)propanoyl]-6H-benzo[b][1,5]benzoxazepine-5-carbohydrazide

InChi Key: LAPNFZVASXLGDW-UHFFFAOYSA-N

InChi Code: InChI=1S/C22H25ClN3O4S/c23-16-8-7-15-13-24-18-5-1-2-6-19(18)30(20(15)12-16)22(28)26-25-21(27)9-11-31-14-17-4-3-10-29-17/h1-4,7-8,10,12-13,18-20,24H,5-6,9,11,14H2,(H,25,27)(H,26,28)

SMILES Code: O=C(O1C2C(C=CC(Cl)=C2)=CNC3C1CC=CC3)NNC(CCSCC4=CC=CO4)=O

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001