Description: Dyphylline is a phosphodiesterase inhibitor used in the treatment of respiratory disorders like asthma, cardiac dyspnea, and bronchitis. Dyphylline is a xanthine derivative with bronchodilator and vasodilator effects. It also acts as an adenosine receptor antagonist. Dyphilline probably acts as a competitive inhibitor of phosphodiesterase which leads to an increase in intracellular cAMP. This results in relaxation of bronchial smooth muscle and other smooth muscles.

Synonym: Dyphylline; Diprophylline; Lufyllin; Corphyllin; Neothylline;

IUPAC/Chemical Name: 7-(2,3-dihydroxypropyl)-1,3-dimethylpurine-2,6-dione

InChi Key: KSCFJBIXMNOVSH-UHFFFAOYSA-N

InChi Code: InChI=1S/C10H14N4O4/c1-12-8-7(9(17)13(2)10(12)18)14(5-11-8)3-6(16)4-15/h5-6,15-16H,3-4H2,1-2H3

SMILES Code: CN1C2=C(C(=O)N(C1=O)C)N(C=N2)CC(CO)O

Appearance: White to off-white crystalline powder.

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO, not in water

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001