产品描述:达沙替尼是非受体酪氨酸激酶Abl和Src以及Src家族其他成员的有效抑制剂。达沙替尼可能对以Abl和Src激酶水平升高为特征的纤维化疾病具有 价值。

产品名称: Dasatinib
CAS#: 302962-49-8 (free)
分子式: C22H26ClN7O2S
分子量: 488.01
元素分析: C, 54.15; H, 5.37; Cl, 7.26; N, 20.09; O, 6.56; S, 6.57

IUPAC/Chemical Name: N-(2-chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyethyl)-1-piperazinyl]-2-methyl-4-pyrimidinyl]amino]-5-thiazolecarboxamide

InChi Key: ZBNZXTGUTAYRHI-UHFFFAOYSA-N

InChi Code: InChI=1S/C22H26ClN7O2S/c1-14-4-3-5-16(23)20(14)28-21(32)17-13-24-22(33-17)27-18-12-19(26-15(2)25-18)30-8-6-29(7-9-30)10-11-31/h3-5,12-13,31H,6-11H2,1-2H3,(H,28,32)(H,24,25,26,27)

SMILES Code: O=C(NC1=C(Cl)C=CC=C1C)C(S2)=CN=C2NC3=NC(C)=NC(N4CCN(CCO)CC4)=C3

Appearance: A crystalline solid

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001