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ACY-1083
  • 品牌:MedKoo
  • 产地:美国
  • 货号:462556
  • cas:1708113-43-2
  • 发布日期: 2022-07-20
  • 更新日期: 2024-08-12
产品详请
产地 美国
品牌 MedKoo
货号 462556
用途 This product is for research use only, not for human or veterinary use.
包装规格 咨询
CAS编号 1708113-43-2
纯度 >98%%
是否进口
Description: ACY-1083 is a selective and brain-penetrating HDAC6 inhibitor and is 260-fold more selective for HDAC6 than all other classes of HDAC isoforms. It effectively reverses chemotherapy-induced peripheral neuropathy.

Synonym: ACY-1083; ACY 1083; ACY1083

IUPAC/Chemical Name: 2-((4,4-difluoro-1-phenylcyclohexyl)amino)-N-hydroxypyrimidine-5-carboxamide

InChi Key: MRWCVKLVSWYIFO-UHFFFAOYSA-N

InChi Code: InChI=1S/C17H18F2N4O2/c18-17(19)8-6-16(7-9-17,13-4-2-1-3-5-13)22-15-20-10-12(11-21-15)14(24)23-25/h1-5,10-11,25H,6-9H2,(H,23,24)(H,20,21,22)

SMILES Code: FC(CC1)(F)CCC1(NC2=NC=C(C(NO)=O)C=N2)C3=CC=CC=C3

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001